Marcoprim Bolus is a potent veterinary antibacterial bolus containing Co-trimoxazole (Sulfamethoxazole + Trimethoprim), designed to combat a wide range of bacterial infections in livestock. Ideal for cattle, buffaloes, goats, and sheep, it treats respiratory infections, diarrhea, urinary tract infections, mastitis, wound infections, and reproductive tract infections. By combining two antibiotics that inhibit bacterial folic acid synthesis at different points, Marcoprim Bolus ensures rapid recovery, reduces stress, and helps maintain herd productivity.
Active Ingredient
Co-trimoxazole – A combination of:
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Sulfamethoxazole – A sulfonamide that inhibits bacterial growth by blocking folic acid synthesis.
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Trimethoprim – Enhances antibacterial effect by inhibiting a different step in folic acid production.
Mechanism: The combination produces a synergistic bactericidal effect, stopping bacterial multiplication and accelerating infection control.
Key Features & Benefits
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Broad-Spectrum Action: Effective against a wide range of bacterial infections.
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Dual Antibiotic Synergy: Enhances antibacterial potency for faster results.
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Promotes Quick Recovery: Reduces downtime and stress in affected animals.
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Reduces Secondary Infections: Protects animals during vulnerable periods.
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Improves Feed Intake & Energy Levels: Helps restore productivity.
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Supports Herd Health: Minimizes economic losses for livestock owners.
Indications / Recommended For
Marcoprim Bolus is used to treat:
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Respiratory infections: Pneumonia, bronchitis
- Diarrhea & enteritis
- Urinary tract infections
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Mastitis in cattle and buffaloes
- Post-surgical infections & abscesses
- Septicemia and general bacterial infections
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Reproductive tract infections: Metritis, post-partum infections
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Wound infections: Cuts, abrasions, and skin lesions
How It Works
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Rapid Absorption: Once administered, Co-trimoxazole enters the bloodstream and reaches infected tissues quickly.
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Dual Inhibition: Sulfamethoxazole and Trimethoprim inhibit bacterial folate metabolism at two separate points.
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Bactericidal Action: The combination kills bacteria rather than just inhibiting growth.
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Faster Recovery: Reduces disease duration, improves appetite, and restores animal health efficiently.
Dosage & Administration
- Administer as per veterinary prescription.
- Usually given orally in bolus form for targeted absorption.
- Ensure clean drinking water is available during treatment.
Storage Instructions
- Store in a cool, dry place away from direct sunlight.
- Keep out of reach of children and non-target animals.
- Keep in original packaging until use.
Possible Side Effects:
- Mild gastrointestinal upset (diarrhea or bloating)
- Temporary loss of appetite
- Rare allergic reactions: Skin rash, restlessness
Precautions:
- Use only under veterinary supervision.
- Avoid in animals allergic to sulfonamides or trimethoprim.
- Do not exceed recommended dose.
- Avoid use in animals with severe liver or kidney disease.
- Ensure animals have adequate water intake during treatment.
- Avoid concurrent use with other sulfonamides unless prescribed.
